| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily KQT member 2 |
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| Ligand | BDBM65950 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel |
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| EC50 | 12400±3750 nM |
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| Citation |  PubChem, PC Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Potassium voltage-gated channel subfamily KQT member 2 |
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| Name: | Potassium voltage-gated channel subfamily KQT member 2 |
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| Synonyms: | KCNQ2_RAT | Kcnq2 | Voltage-gated potassium channel subunit Kv7.2 | potassium voltage-gated channel, KQT-like subfamily, member 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93984.01 |
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| Organism: | Rattus norvegicus |
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| Description: | EBI_100117 |
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| Residue: | 852 |
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| Sequence: | MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
QYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVS
LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRI
KGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDP
SMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSR
DHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLV
RIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELER
SFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEG
PFGDVAWAGPRK
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| BDBM65950 |
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| n/a |
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| Name | BDBM65950 |
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| Synonyms: | 1-(3-fluorophenyl)-3-(5-methyl-3-pyridinyl)urea;2,2,2-trifluoroacetic acid | 1-(3-fluorophenyl)-3-(5-methyl-3-pyridyl)urea;2,2,2-trifluoroacetic acid | 1-(3-fluorophenyl)-3-(5-methylpyridin-3-yl)urea;2,2,2-trifluoroacetic acid | 1-(3-fluorophenyl)-3-(5-methylpyridin-3-yl)urea;2,2,2-tris(fluoranyl)ethanoic acid | VU0417943-1 | cid_45489579 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12FN3O |
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| Mol. Mass. | 245.2523 |
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| SMILES | Cc1cncc(NC(=O)Nc2cccc(F)c2)c1 |
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| Structure | 
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