| Reaction Details |
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 | Report a problem with these data |
| Target | Vacuolar aminopeptidase 1 |
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| Ligand | BDBM64560 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits |
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| EC50 | 2455±n/a nM |
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| Citation |  PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Vacuolar aminopeptidase 1 |
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| Name: | Vacuolar aminopeptidase 1 |
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| Synonyms: | AMPL_YEAST | APE1 | API | LAP4 | YSC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57084.90 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | gi_486173 |
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| Residue: | 514 |
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| Sequence: | MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI
YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW
RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL
YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE
PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP
RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER
SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM
ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS
IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
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| BDBM64560 |
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| n/a |
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| Name | BDBM64560 |
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| Synonyms: | (5,7-dichloroquinolin-8-yl) furan-2-carboxylate | 2-furancarboxylic acid (5,7-dichloro-8-quinolinyl) ester | Furan-2-carboxylic acid 5,7-dichloro-quinolin-8-yl ester | MLS000526478 | SMR000116952 | [5,7-bis(chloranyl)quinolin-8-yl] furan-2-carboxylate | cid_686057 | furan-2-carboxylic acid (5,7-dichloro-8-quinolyl) ester |
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| Type | Small organic molecule |
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| Emp. Form. | C14H7Cl2NO3 |
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| Mol. Mass. | 308.116 |
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| SMILES | Clc1cc(Cl)c2cccnc2c1OC(=O)c1ccco1 |
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| Structure | 
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