| Reaction Details |
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 | Report a problem with these data |
| Target | Vacuolar aminopeptidase 1 |
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| Ligand | BDBM66043 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits |
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| EC50 | 4424±n/a nM |
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| Citation |  PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Vacuolar aminopeptidase 1 |
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| Name: | Vacuolar aminopeptidase 1 |
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| Synonyms: | AMPL_YEAST | APE1 | API | LAP4 | YSC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57084.90 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | gi_486173 |
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| Residue: | 514 |
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| Sequence: | MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI
YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW
RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL
YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE
PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP
RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER
SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM
ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS
IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
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| BDBM66043 |
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| n/a |
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| Name | BDBM66043 |
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| Synonyms: | 2-hydroxy-3-[(E)-3-(2-hydroxy-3-methoxy-phenyl)acryloyl]-6-methyl-pyran-4-one | 2-hydroxy-3-[(E)-3-(2-hydroxy-3-methoxyphenyl)-1-oxoprop-2-enyl]-6-methyl-4-pyranone | 2-hydroxy-3-[(E)-3-(2-hydroxy-3-methoxyphenyl)prop-2-enoyl]-6-methylpyran-4-one | 3-[(E)-3-(3-methoxy-2-oxidanyl-phenyl)prop-2-enoyl]-6-methyl-2-oxidanyl-pyran-4-one | 4-hydroxy-3-[3-(2-hydroxy-3-methoxyphenyl)acryloyl]-6-methyl-2H-pyran-2-one | MLS000530155 | SMR000135132 | cid_5717503 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14O6 |
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| Mol. Mass. | 302.2788 |
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| SMILES | COc1cccc(C=CC(=O)c2c(O)cc(C)oc2=O)c1O |w:7.6| |
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| Structure | 
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