| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vacuolar aminopeptidase 1 |
|---|
| Ligand | BDBM66013 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits |
|---|
| EC50 | 1318±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Vacuolar aminopeptidase 1 |
|---|
| Name: | Vacuolar aminopeptidase 1 |
|---|
| Synonyms: | AMPL_YEAST | APE1 | API | LAP4 | YSC1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 57084.90 |
|---|
| Organism: | Saccharomyces cerevisiae |
|---|
| Description: | gi_486173 |
|---|
| Residue: | 514 |
|---|
| Sequence: | MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI
YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW
RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL
YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE
PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP
RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER
SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM
ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS
IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
|
|
|
|---|
| BDBM66013 |
|---|
| n/a |
|---|
| Name | BDBM66013 |
|---|
| Synonyms: | (5E)-1-(4-methoxyphenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-diazinane-4,6-dione | (5E)-1-(4-methoxyphenyl)-5-(2-thenylidene)-2-thioxo-hexahydropyrimidine-4,6-quinone | 1-(4-Methoxy-phenyl)-5-[1-thiophen-2-yl-meth-(E)-ylidene]-2-thioxo-dihydro-pyrimidine-4,6-dione | MLS000768270 | SMR000431591 | cid_1602504 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H12N2O3S2 |
|---|
| Mol. Mass. | 344.408 |
|---|
| SMILES | COc1ccc(cc1)N1C(=S)NC(=O)C(=Cc2cccs2)C1=O |w:15.16| |
|---|
| Structure | 
|
|---|
Search and Browse
