| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM66109 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase |
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| IC50 | 13428±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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|
|
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| BDBM66109 |
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| n/a |
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| Name | BDBM66109 |
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| Synonyms: | 2-(3-Furan-2-yl-4-methyl-pentyl)-isoindole-1,3-dione | 2-[3-(2-furanyl)-4-methylpentyl]isoindole-1,3-dione | 2-[3-(2-furyl)-4-methyl-pentyl]isoindoline-1,3-quinone | 2-[3-(furan-2-yl)-4-methyl-pentyl]isoindole-1,3-dione | 2-[3-(furan-2-yl)-4-methylpentyl]isoindole-1,3-dione | MLS000557321 | SMR000148238 | cid_4418419 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19NO3 |
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| Mol. Mass. | 297.3484 |
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| SMILES | CC(C)C(CCN1C(=O)c2ccccc2C1=O)c1ccco1 |
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| Structure | 
|
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