Reaction Details |
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Target | Beta-lactamase |
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Ligand | BDBM47591 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase |
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IC50 | >59640±n/a nM |
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Citation | PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Beta-lactamase |
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Name: | Beta-lactamase |
Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 27125.88 |
Organism: | Pseudomonas aeruginosa |
Description: | gi_27368096 |
Residue: | 246 |
Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
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BDBM47591 |
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n/a |
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Name | BDBM47591 |
Synonyms: | (6'-acetyloxy-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-3'-yl) ethanoate | (6'-acetyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl) acetate | MLS000722997 | SMR000236387 | acetic acid (6'-acetoxy-3-keto-spiro[phthalan-1,9'-xanthene]-3'-yl) ester | acetic acid (6'-acetyloxy-3-oxo-3'-spiro[isobenzofuran-1,9'-xanthene]yl) ester | cid_65047 |
Type | Small organic molecule |
Emp. Form. | C24H16O7 |
Mol. Mass. | 416.3796 |
SMILES | CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C22OC(=O)c3ccccc23)c1 |
Structure |
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