BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBcl-2-like protein 11
LigandBDBM39730
Substrate/Competitorn/a
Meas. Tech.Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50 5842±n/a nM
Citation PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-like protein 11
Name:Bcl-2-like protein 11
Synonyms:B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:PROTEIN
Mol. Mass.:22175.26
Organism:Homo sapiens (Human)
Description:EBI_101325
Residue:198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39730
n/a
NameBDBM39730
Synonyms:2-(1-naphthalenyl)-N-[2,2,2-trichloro-1-[[(2,5-dimethylanilino)-sulfanylidenemethyl]amino]ethyl]acetamide | 2-(1-naphthyl)-N-[2,2,2-trichloro-1-({[(2,5-dimethylphenyl)amino]carbonothioyl}amino)ethyl]acetamide | 2-(1-naphthyl)-N-[2,2,2-trichloro-1-[(2,5-dimethylphenyl)thiocarbamoylamino]ethyl]acetamide | 2-naphthalen-1-yl-N-[2,2,2-trichloro-1-[(2,5-dimethylphenyl)carbamothioylamino]ethyl]acetamide | 2-naphthalen-1-yl-N-[2,2,2-tris(chloranyl)-1-[(2,5-dimethylphenyl)carbamothioylamino]ethyl]ethanamide | MLS000532149 | SMR000137090 | cid_2831455
TypeSmall organic molecule
Emp. Form.C23H22Cl3N3OS
Mol. Mass.494.864
SMILESCc1ccc(C)c(NC(=S)NC(NC(=O)Cc2cccc3ccccc23)C(Cl)(Cl)Cl)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: