| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 11 |
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| Ligand | BDBM66374 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis |
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| EC50 | 5353±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-like protein 11 |
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| Name: | Bcl-2-like protein 11 |
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| Synonyms: | B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22175.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101325 |
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| Residue: | 198 |
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| Sequence: | MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
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| BDBM66374 |
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| n/a |
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| Name | BDBM66374 |
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| Synonyms: | 2-[(4-chlorobenzoyl)amino]-4-methyl-valeric acid [2-keto-2-(3-keto-4H-1,4-benzoxazin-6-yl)ethyl] ester | 2-[[(4-chlorophenyl)-oxomethyl]amino]-4-methylpentanoic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester | MLS000571077 | SMR000150696 | [2-oxidanylidene-2-(3-oxidanylidene-4H-1,4-benzoxazin-6-yl)ethyl] 2-[(4-chlorophenyl)carbonylamino]-4-methyl-pentanoate | [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2-[(4-chlorobenzoyl)amino]-4-methylpentanoate | cid_3930624 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23ClN2O6 |
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| Mol. Mass. | 458.892 |
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| SMILES | CC(C)CC(NC(=O)c1ccc(Cl)cc1)C(=O)OCC(=O)c1ccc2OCC(=O)Nc2c1 |
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| Structure | 
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