Reaction Details |
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Target | Bcl-2-like protein 11 |
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Ligand | BDBM63166 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis |
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EC50 | 5243±n/a nM |
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Citation | PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Bcl-2-like protein 11 |
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Name: | Bcl-2-like protein 11 |
Synonyms: | B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM |
Type: | PROTEIN |
Mol. Mass.: | 22175.26 |
Organism: | Homo sapiens (Human) |
Description: | EBI_101325 |
Residue: | 198 |
Sequence: | MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
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BDBM63166 |
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n/a |
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Name | BDBM63166 |
Synonyms: | MLS000586455 | N-butyl-4-[(4-keto-8-methoxy-2-thioxo-1,5-dihydropyrimid[5,4-b]indol-3-yl)methyl]benzamide | N-butyl-4-[(8-methoxy-4-oxidanylidene-2-sulfanylidene-1,5-dihydropyrimido[5,4-b]indol-3-yl)methyl]benzamide | N-butyl-4-[(8-methoxy-4-oxo-2-sulfanylidene-1,5-dihydropyrimido[5,4-b]indol-3-yl)methyl]benzamide | N-butyl-4-[(8-methoxy-4-oxo-2-thioxo-1,2,4,5-tetrahydro-3H-pyrimido[5,4-b]indol-3-yl)methyl]benzamide | SMR000207834 | cid_12004488 |
Type | Small organic molecule |
Emp. Form. | C23H24N4O3S |
Mol. Mass. | 436.527 |
SMILES | CCCCNC(=O)c1ccc(Cn2c(=S)[nH]c3c4cc(OC)ccc4[nH]c3c2=O)cc1 |
Structure |
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