| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 11 |
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| Ligand | BDBM61056 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis |
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| EC50 | 8615±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-like protein 11 |
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| Name: | Bcl-2-like protein 11 |
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| Synonyms: | B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22175.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101325 |
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| Residue: | 198 |
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| Sequence: | MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
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|
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| BDBM61056 |
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| n/a |
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| Name | BDBM61056 |
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| Synonyms: | 3-Amino-6-trifluoromethoxy-thieno[2,3-b]quinoline-2-carboxylic acid [4-(pyrrolidine-1-sulfonyl)-phenyl]-amide | 3-amino-N-(4-pyrrolidin-1-ylsulfonylphenyl)-6-(trifluoromethoxy)thieno[2,3-b]quinoline-2-carboxamide | 3-amino-N-(4-pyrrolidinosulfonylphenyl)-6-(trifluoromethoxy)thieno[2,3-b]quinoline-2-carboxamide | 3-amino-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-6-(trifluoromethoxy)-2-thieno[2,3-b]quinolinecarboxamide | 3-azanyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)-6-(trifluoromethyloxy)thieno[2,3-b]quinoline-2-carboxamide | MLS000553472 | SMR000171173 | cid_3231291 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19F3N4O4S2 |
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| Mol. Mass. | 536.547 |
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| SMILES | Nc1c(sc2nc3ccc(OC(F)(F)F)cc3cc12)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCCC1 |
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| Structure | 
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