| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 11 |
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| Ligand | BDBM66483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis |
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| EC50 | 5696±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-like protein 11 |
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| Name: | Bcl-2-like protein 11 |
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| Synonyms: | B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22175.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101325 |
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| Residue: | 198 |
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| Sequence: | MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
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| BDBM66483 |
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| n/a |
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| Name | BDBM66483 |
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| Synonyms: | 2-[2-[[(E)-[1,3-diketo-2-[3-(trifluoromethyl)phenyl]-4-isoquinolylidene]methyl]amino]thiazol-4-yl]acetic acid methyl ester | 2-[2-[[(E)-[1,3-dioxo-2-[3-(trifluoromethyl)phenyl]-4-isoquinolinylidene]methyl]amino]-4-thiazolyl]acetic acid methyl ester | MLS000334526 | SMR000249284 | cid_6216333 | methyl 2-[2-[[(E)-[1,3-bis(oxidanylidene)-2-[3-(trifluoromethyl)phenyl]isoquinolin-4-ylidene]methyl]amino]-1,3-thiazol-4-yl]ethanoate | methyl 2-[2-[[(E)-[1,3-dioxo-2-[3-(trifluoromethyl)phenyl]isoquinolin-4-ylidene]methyl]amino]-1,3-thiazol-4-yl]acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C23H16F3N3O4S |
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| Mol. Mass. | 487.451 |
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| SMILES | COC(=O)Cc1csc(N=Cc2c(O)n(-c3cccc(c3)C(F)(F)F)c(=O)c3ccccc23)n1 |w:9.8| |
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| Structure | 
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