| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 11 |
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| Ligand | BDBM66507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis |
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| EC50 | 3130±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-like protein 11 |
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| Name: | Bcl-2-like protein 11 |
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| Synonyms: | B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22175.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101325 |
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| Residue: | 198 |
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| Sequence: | MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
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|
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| BDBM66507 |
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| n/a |
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| Name | BDBM66507 |
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| Synonyms: | 2-[5-(4-cyanobenzylidene)-3-[2-(2,3-dimethylanilino)-2-keto-ethyl]-4-keto-thiazolidin-2-ylidene]acetic acid ethyl ester | 2-[5-[(4-cyanophenyl)methylidene]-3-[2-(2,3-dimethylanilino)-2-oxoethyl]-4-oxo-2-thiazolidinylidene]acetic acid ethyl ester | MLS000394606 | SMR000262046 | cid_4882012 | ethyl 2-[5-[(4-cyanophenyl)methylidene]-3-[2-(2,3-dimethylanilino)-2-oxoethyl]-4-oxo-1,3-thiazolidin-2-ylidene]acetate | ethyl 2-[5-[(4-cyanophenyl)methylidene]-3-[2-[(2,3-dimethylphenyl)amino]-2-oxidanylidene-ethyl]-4-oxidanylidene-1,3-thiazolidin-2-ylidene]ethanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C25H23N3O4S |
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| Mol. Mass. | 461.533 |
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| SMILES | CCOC(=O)C=c1sc(=Cc2ccc(cc2)C#N)c(=O)n1CC(=O)Nc1cccc(C)c1C |
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| Structure | 
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