| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 11 |
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| Ligand | BDBM58065 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis |
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| EC50 | 50430±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-like protein 11 |
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| Name: | Bcl-2-like protein 11 |
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| Synonyms: | B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22175.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101325 |
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| Residue: | 198 |
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| Sequence: | MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
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|
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| BDBM58065 |
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| n/a |
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| Name | BDBM58065 |
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| Synonyms: | (4E)-4-[[2-[2-(3,5-dimethylpyrazol-1-yl)-6-methyl-pyrimidin-4-yl]hydrazinyl]methylidene]-2-ethoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[2-[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]hydrazinyl]methylidene]-2-ethoxycyclohexa-2,5-dien-1-one | (4E)-4-[[N'-[2-(3,5-dimethylpyrazol-1-yl)-6-methyl-pyrimidin-4-yl]hydrazino]methylene]-2-ethoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[[2-(3,5-dimethyl-1-pyrazolyl)-6-methyl-4-pyrimidinyl]hydrazo]methylidene]-2-ethoxy-1-cyclohexa-2,5-dienone | 4-{[2-(3,5-Dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-hydrazonomethyl}-2-ethoxy-phenol | MLS000777513 | SMR000413907 | cid_6525018 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N6O2 |
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| Mol. Mass. | 366.417 |
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| SMILES | CCOc1cc(CN=Nc2cc(C)nc(n2)-n2nc(C)cc2C)ccc1O |w:8.8| |
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| Structure | 
|
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