BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBcl-2-like protein 11
LigandBDBM61114
Substrate/Competitorn/a
Meas. Tech.Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50 5770±n/a nM
Citation PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-like protein 11
Name:Bcl-2-like protein 11
Synonyms:B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:PROTEIN
Mol. Mass.:22175.26
Organism:Homo sapiens (Human)
Description:EBI_101325
Residue:198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM61114
n/a
NameBDBM61114
Synonyms:2,6-di-tert-butyl-4-(3,4-dimethoxybenzylidene)-2,5-cyclohexadien-1-one | 2,6-ditert-butyl-4-[(3,4-dimethoxyphenyl)methylidene]-1-cyclohexa-2,5-dienone | 2,6-ditert-butyl-4-[(3,4-dimethoxyphenyl)methylidene]cyclohexa-2,5-dien-1-one | 2,6-ditert-butyl-4-veratrylidene-cyclohexa-2,5-dien-1-one | MLS001163486 | SMR000496761 | cid_2868490
TypeSmall organic molecule
Emp. Form.C23H30O3
Mol. Mass.354.4825
SMILES[#6]-[#8]-c1ccc(\[#6]=[#6]-2\[#6]=[#6](-[#6](=O)-[#6](=[#6]-2)C([#6])([#6])[#6])C([#6])([#6])[#6])cc1-[#8]-[#6] |c:8,12|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: