BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBcl-2-like protein 11
LigandBDBM50063753
Substrate/Competitorn/a
Meas. Tech.Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50>350000±n/a nM
Citation PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-like protein 11
Name:Bcl-2-like protein 11
Synonyms:B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:PROTEIN
Mol. Mass.:22175.26
Organism:Homo sapiens (Human)
Description:EBI_101325
Residue:198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50063753
n/a
NameBDBM50063753
Synonyms:CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide | N-{5-Chloro-4-[(4-chloro-phenyl)-cyano-methyl]-2-methyl-phenyl}-2-hydroxy-3,5-diiodo-benzamide | cid_42574
TypeSmall organic molecule
Emp. Form.C22H14Cl2I2N2O2
Mol. Mass.663.074
SMILESCc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: