Reaction Details |
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Target | Apelin receptor |
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Ligand | BDBM38993 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay |
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IC50 | 9670±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS hits from a small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Apelin receptor |
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Name: | Apelin receptor |
Synonyms: | AGTRL1 | APJ | APJ_HUMAN | APLNR | Angiotensin receptor-like 1 | Apelin receptor | Apelin receptor (APJ) | G-protein coupled receptor APJ | G-protein coupled receptor HG11 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 42664.06 |
Organism: | Homo sapiens (Human) |
Description: | P35414 |
Residue: | 380 |
Sequence: | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK
RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL
TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ
CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL
RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV
NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK
GGEQMHEKSIPYSQETLVVD
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BDBM38993 |
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n/a |
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Name | BDBM38993 |
Synonyms: | (1Z,3Z)-1,4-bis(butylsulfonyl)buta-1,3-diene | MLS000085704 | SMR000020833 | cid_5286934 |
Type | Small organic molecule |
Emp. Form. | C12H22O4S2 |
Mol. Mass. | 294.431 |
SMILES | CCCCS(=O)(=O)\C=C/C=C\S(=O)(=O)CCCC |
Structure |
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