Ki Summary

Reaction Details

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Target

Female germline-specific tumor suppressor gld-1

Ligand

BDBM51067

Substrate/Competitor

n/a

Meas. Tech.

Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction

IC50

1961±n/a nM

Citation

PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Female germline-specific tumor suppressor gld-1

Name:

Female germline-specific tumor suppressor gld-1

Synonyms:

GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

50591.33

Organism:

Caenorhabditis elegans

Description:

gi_17507875

Residue:

463

Sequence:

MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRR
DGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATP
MSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGR
VRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDT
GCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKK
LLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSP
TPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPT
TTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF

BDBM51067

n/a

Name

BDBM51067

Synonyms:

3-aminobenzoic acid [2-[(9,10-diketo-1-anthryl)amino]-2-keto-ethyl] ester | 3-aminobenzoic acid [2-[(9,10-dioxo-1-anthracenyl)amino]-2-oxoethyl] ester | MLS000334016 | SMR000248774 | [2-[(9,10-dioxoanthracen-1-yl)amino]-2-oxoethyl] 3-aminobenzoate | [2-[[9,10-bis(oxidanylidene)anthracen-1-yl]amino]-2-oxidanylidene-ethyl] 3-azanylbenzoate | cid_4009020

Type

Small organic molecule

Emp. Form.

C23H16N2O5

Mol. Mass.

400.3835

SMILES

Nc1cccc(c1)C(=O)OCC(=O)Nc1cccc2C(=O)c3ccccc3C(=O)c12

Structure