| Reaction Details |
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 | Report a problem with these data |
| Target | Guanine nucleotide-binding protein G(o) subunit alpha |
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| Ligand | BDBM67701 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao with additional round of SAR compounds |
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| EC50 | >30000±0 nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao with additional round of SAR compounds PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Guanine nucleotide-binding protein G(o) subunit alpha |
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| Name: | Guanine nucleotide-binding protein G(o) subunit alpha |
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| Synonyms: | GNAO1 | GNAO_HUMAN | Guanine nucleotide-binding protein G(o), alpha subunit 1 | guanine nucleotide-binding protein G(o) subunit alpha isoform a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40043.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_321106 |
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| Residue: | 354 |
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| Sequence: | MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
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| BDBM67701 |
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| n/a |
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| Name | BDBM67701 |
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| Synonyms: | 3-chloranyl-6-methyl-N-(3-morpholin-4-ylpropyl)-1-benzothiophene-2-carboxamide | 3-chloro-6-methyl-N-(3-morpholin-4-ylpropyl)-1-benzothiophene-2-carboxamide | 3-chloro-6-methyl-N-(3-morpholinopropyl)benzothiophene-2-carboxamide | 3-chloro-6-methyl-N-[3-(4-morpholinyl)propyl]-1-benzothiophene-2-carboxamide | KSC-1-101c | KUC103874N | cid_3579902 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21ClN2O2S |
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| Mol. Mass. | 352.879 |
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| SMILES | Cc1ccc2c(Cl)c(sc2c1)C(=O)NCCCN1CCOCC1 |
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| Structure | 
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