Reaction Details |
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Target | Guanine nucleotide-binding protein G(o) subunit alpha |
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Ligand | BDBM67701 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao with additional round of SAR compounds. |
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EC50 | >30000±0 nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao with additional round of SAR compounds. PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Guanine nucleotide-binding protein G(o) subunit alpha |
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Name: | Guanine nucleotide-binding protein G(o) subunit alpha |
Synonyms: | GNAO1 | GNAO_HUMAN | Guanine nucleotide-binding protein G(o), alpha subunit 1 | guanine nucleotide-binding protein G(o) subunit alpha isoform a |
Type: | PROTEIN |
Mol. Mass.: | 40043.59 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_321106 |
Residue: | 354 |
Sequence: | MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
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BDBM67701 |
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n/a |
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Name | BDBM67701 |
Synonyms: | 3-chloranyl-6-methyl-N-(3-morpholin-4-ylpropyl)-1-benzothiophene-2-carboxamide | 3-chloro-6-methyl-N-(3-morpholin-4-ylpropyl)-1-benzothiophene-2-carboxamide | 3-chloro-6-methyl-N-(3-morpholinopropyl)benzothiophene-2-carboxamide | 3-chloro-6-methyl-N-[3-(4-morpholinyl)propyl]-1-benzothiophene-2-carboxamide | KSC-1-101c | KUC103874N | cid_3579902 |
Type | Small organic molecule |
Emp. Form. | C17H21ClN2O2S |
Mol. Mass. | 352.879 |
SMILES | Cc1ccc2c(Cl)c(sc2c1)C(=O)NCCCN1CCOCC1 |
Structure |
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