| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM39089 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | 350±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
|
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| BDBM39089 |
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| n/a |
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| Name | BDBM39089 |
|---|
| Synonyms: | 2-(5-bromanyl-2-chloranyl-phenyl)-1,3-benzoxazol-5-amine | 2-(5-bromo-2-chlorophenyl)-1,3-benzoxazol-5-amine | MLS000036810 | SMR000036737 | [2-(5-bromo-2-chloro-phenyl)-1,3-benzoxazol-5-yl]amine | cid_659499 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C13H8BrClN2O |
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| Mol. Mass. | 323.572 |
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| SMILES | Nc1ccc2oc(nc2c1)-c1cc(Br)ccc1Cl |
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| Structure | 
|
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