Ki Summary

Reaction Details

Report a problem with these data

Target

DNA damage-inducible transcript 3 protein

Ligand

BDBM41384

Substrate/Competitor

n/a

Meas. Tech.

Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress

IC50

>10000±n/a nM

Citation

PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

DNA damage-inducible transcript 3 protein

Name:

DNA damage-inducible transcript 3 protein

Synonyms:

Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153

Type:

Enzyme Catalytic Domain

Mol. Mass.:

19175.17

Organism:

Mus musculus

Description:

gi_160707929

Residue:

168

Sequence:

MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA

BDBM41384

n/a

Name

BDBM41384

Synonyms:

MLS000042033 | N-[(1S,2R)-1-[5-(2,5-dimethylbenzyl)sulfonyl-1,3,4-oxadiazol-2-yl]-2-methyl-butyl]carbamic acid tert-butyl ester | N-[(1S,2R)-1-[5-[(2,5-dimethylphenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]-2-methylbutyl]carbamic acid tert-butyl ester | SMR000045309 | cid_664366 | tert-butyl N-[(1S,2R)-1-[5-[(2,5-dimethylphenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]-2-methyl-butyl]carbamate | tert-butyl N-[(1S,2R)-1-[5-[(2,5-dimethylphenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]-2-methylbutyl]carbamate

Type

Small organic molecule

Emp. Form.

C21H31N3O5S

Mol. Mass.

437.553

SMILES

CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)c1nnc(o1)S(=O)(=O)Cc1cc(C)ccc1C

Structure