Reaction Details |
| Report a problem with these data |
Target | DNA damage-inducible transcript 3 protein |
---|
Ligand | BDBM41599 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
---|
IC50 | <160±n/a nM |
---|
Citation | PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
DNA damage-inducible transcript 3 protein |
---|
Name: | DNA damage-inducible transcript 3 protein |
Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 19175.17 |
Organism: | Mus musculus |
Description: | gi_160707929 |
Residue: | 168 |
Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
|
|
|
BDBM41599 |
---|
n/a |
---|
Name | BDBM41599 |
Synonyms: | (E)-[1-[4-(4-chlorobenzyl)oxyphenyl]-2,5-dimethyl-pyrrol-3-yl]methylene-(1,2,4-triazol-4-yl)amine | 1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethyl-3-pyrrolyl]-N-(1,2,4-triazol-4-yl)methanimine | 1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethyl-pyrrol-3-yl]-N-(1,2,4-triazol-4-yl)methanimine | 1-[1-[4-[(4-chlorophenyl)methoxy]phenyl]-2,5-dimethylpyrrol-3-yl]-N-(1,2,4-triazol-4-yl)methanimine | MLS000534371 | N-[(1-{4-[(4-chlorobenzyl)oxy]phenyl}-2,5-dimethyl-1H-pyrrol-3-yl)methylene]-4H-1,2,4-triazol-4-amine | SMR000141803 | [1-[4-(4-chlorobenzyl)oxyphenyl]-2,5-dimethyl-pyrrol-3-yl]methylene-(1,2,4-triazol-4-yl)amine | cid_1282232 |
Type | Small organic molecule |
Emp. Form. | C22H20ClN5O |
Mol. Mass. | 405.88 |
SMILES | Cc1cc(C=Nn2cnnc2)c(C)n1-c1ccc(OCc2ccc(Cl)cc2)cc1 |w:5.5| |
Structure |
|