| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM67887 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | 4190±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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| BDBM67887 |
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| n/a |
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| Name | BDBM67887 |
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| Synonyms: | 4-({2-[(2,4-dichlorobenzyl)oxy]-3-ethoxybenzyl}amino)phenol | 4-[[2-(2,4-dichlorobenzyl)oxy-3-ethoxy-benzyl]amino]phenol | 4-[[2-[(2,4-dichlorophenyl)methoxy]-3-ethoxy-phenyl]methylamino]phenol | 4-[[2-[(2,4-dichlorophenyl)methoxy]-3-ethoxyphenyl]methylamino]phenol | MLS000540075 | SMR000162389 | cid_1807334 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21Cl2NO3 |
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| Mol. Mass. | 418.313 |
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| SMILES | CCOc1cccc(CNc2ccc(O)cc2)c1OCc1ccc(Cl)cc1Cl |
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| Structure | 
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