| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM62439 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | 170±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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| BDBM62439 |
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| n/a |
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| Name | BDBM62439 |
|---|
| Synonyms: | MLS000570595 | N'-[3-(1,3-benzodioxol-5-yl)-2-propen-1-ylidene]-2-(2,3-dimethylphenoxy)acetohydrazide | N-[[(E)-3-(1,3-benzodioxol-5-yl)prop-2-enylidene]amino]-2-(2,3-dimethylphenoxy)acetamide | N-[[(E)-3-(1,3-benzodioxol-5-yl)prop-2-enylidene]amino]-2-(2,3-dimethylphenoxy)ethanamide | SMR000187020 | cid_2263315 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N2O4 |
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| Mol. Mass. | 352.3838 |
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| SMILES | Cc1cccc(OCC(=O)NN=C\C=C\c2ccc3OCOc3c2)c1C |
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| Structure | 
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