Reaction Details |
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Target | DNA damage-inducible transcript 3 protein |
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Ligand | BDBM32851 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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IC50 | 1840±n/a nM |
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Citation | PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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DNA damage-inducible transcript 3 protein |
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Name: | DNA damage-inducible transcript 3 protein |
Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 19175.17 |
Organism: | Mus musculus |
Description: | gi_160707929 |
Residue: | 168 |
Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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BDBM32851 |
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n/a |
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Name | BDBM32851 |
Synonyms: | (1,3-dioxoisoindol-2-yl) 2,4,5-trimethylbenzenesulfonate | 2,4,5-trimethylbenzenesulfonic acid (1,3-dioxo-2-isoindolyl) ester | 2,4,5-trimethylbenzenesulfonic acid phthalimido ester | 2-{[(2,4,5-trimethylphenyl)sulfonyl]oxy}-1H-isoindole-1,3(2H)-dione | MLS000577081 | SMR000198161 | [1,3-bis(oxidanylidene)isoindol-2-yl] 2,4,5-trimethylbenzenesulfonate | cid_1582613 |
Type | Small organic molecule |
Emp. Form. | C17H15NO5S |
Mol. Mass. | 345.37 |
SMILES | Cc1cc(C)c(cc1C)S(=O)(=O)ON1C(=O)c2ccccc2C1=O |
Structure |
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