| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM45041 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | 5310±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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| BDBM45041 |
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| n/a |
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| Name | BDBM45041 |
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| Synonyms: | 3-(2-naphthalenyl)-N-(2-pyridinylmethylideneamino)-1H-pyrazole-5-carboxamide | 3-(2-naphthyl)-N'-(2-pyridinylmethylene)-1H-pyrazole-5-carbohydrazide | 3-(2-naphthyl)-N-(2-pyridylmethyleneamino)-1H-pyrazole-5-carboxamide | 3-(2-naphthyl)-N-[(E)-2-pyridylmethyleneamino]-1H-pyrazole-5-carboxamide | 3-naphthalen-2-yl-N-(pyridin-2-ylmethylideneamino)-1H-pyrazole-5-carboxamide | MLS000577741 | SMR000187124 | cid_687713 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H15N5O |
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| Mol. Mass. | 341.366 |
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| SMILES | O=C(NN=Cc1ccccn1)c1cc(n[nH]1)-c1ccc2ccccc2c1 |w:3.2| |
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| Structure | 
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