Reaction Details |
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Target | DNA damage-inducible transcript 3 protein |
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Ligand | BDBM67975 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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IC50 | 6100±n/a nM |
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Citation | PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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DNA damage-inducible transcript 3 protein |
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Name: | DNA damage-inducible transcript 3 protein |
Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 19175.17 |
Organism: | Mus musculus |
Description: | gi_160707929 |
Residue: | 168 |
Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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BDBM67975 |
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n/a |
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Name | BDBM67975 |
Synonyms: | 1-[3-chloro-4-(difluoromethoxy)phenyl]-3-(4-nitrophenyl)urea | 1-[4-[bis(fluoranyl)methoxy]-3-chloranyl-phenyl]-3-(4-nitrophenyl)urea | MLS000581434 | N-[3-chloro-4-(difluoromethoxy)phenyl]-N'-(4-nitrophenyl)urea | SMR000200059 | cid_2957586 |
Type | Small organic molecule |
Emp. Form. | C14H10ClF2N3O4 |
Mol. Mass. | 357.697 |
SMILES | [O-][N+](=O)c1ccc(NC(=O)Nc2ccc(OC(F)F)c(Cl)c2)cc1 |
Structure |
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