| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM49581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | 2780±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
|
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| BDBM49581 |
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| n/a |
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| Name | BDBM49581 |
|---|
| Synonyms: | 2-hydroxy-6-methoxy-1H-benzo[de]isoquinoline-1,3(2H)-dione | 2-hydroxy-6-methoxy-benzo[de]isoquinoline-1,3-quinone | 2-hydroxy-6-methoxybenzo[de]isoquinoline-1,3-dione | 6-methoxy-2-oxidanyl-benzo[de]isoquinoline-1,3-dione | MLS000583698 | SMR000200026 | cid_2210746 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9NO4 |
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| Mol. Mass. | 243.2149 |
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| SMILES | COc1ccc2C(=O)N(O)C(=O)c3cccc1c23 |
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| Structure | 
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