| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM67993 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | >10000±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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| BDBM67993 |
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| n/a |
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| Name | BDBM67993 |
|---|
| Synonyms: | (Z)-3-(1,3-diphenyl-4-pyrazolyl)-N-(2-thiazolyl)-2-propenamide | (Z)-3-(1,3-diphenylpyrazol-4-yl)-N-(1,3-thiazol-2-yl)prop-2-enamide | (Z)-3-(1,3-diphenylpyrazol-4-yl)-N-thiazol-2-yl-acrylamide | 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N-1,3-thiazol-2-ylacrylamide | MLS000573573 | SMR000195362 | cid_2173119 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16N4OS |
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| Mol. Mass. | 372.443 |
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| SMILES | O=C(Nc1nccs1)\C=C/c1cn(nc1-c1ccccc1)-c1ccccc1 |
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| Structure | 
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