| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM68014 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | 6960±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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| BDBM68014 |
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| n/a |
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| Name | BDBM68014 |
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| Synonyms: | 4-chloranyl-N-[2-[(4-chlorophenyl)amino]-2-phenyl-ethyl]benzenesulfonamide | 4-chloro-N-[2-(4-chloroanilino)-2-phenyl-ethyl]benzenesulfonamide | 4-chloro-N-[2-(4-chloroanilino)-2-phenylethyl]benzenesulfonamide | 4-chloro-N-{2-[(4-chlorophenyl)amino]-2-phenylethyl}benzenesulfonamide | MLS000586486 | SMR000207865 | cid_4082378 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18Cl2N2O2S |
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| Mol. Mass. | 421.34 |
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| SMILES | Clc1ccc(NC(CNS(=O)(=O)c2ccc(Cl)cc2)c2ccccc2)cc1 |
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| Structure | 
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