| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM68063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | 9730±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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| BDBM68063 |
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| n/a |
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| Name | BDBM68063 |
|---|
| Synonyms: | MLS000333952 | N-[(1S)-1-(1H-benzimidazol-2-yl)-2-phenyl-ethyl]-2-(4-chloranyl-2-methyl-phenoxy)ethanamide | N-[(1S)-1-(1H-benzimidazol-2-yl)-2-phenyl-ethyl]-2-(4-chloro-2-methyl-phenoxy)acetamide | N-[(1S)-1-(1H-benzimidazol-2-yl)-2-phenylethyl]-2-(4-chloro-2-methylphenoxy)acetamide | SMR000248710 | cid_2103800 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22ClN3O2 |
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| Mol. Mass. | 419.903 |
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| SMILES | Cc1cc(Cl)ccc1OCC(=O)N[C@@H](Cc1ccccc1)c1nc2ccccc2[nH]1 |
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| Structure | 
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