| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM68097 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | >10000±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
|
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| BDBM68097 |
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| n/a |
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| Name | BDBM68097 |
|---|
| Synonyms: | MLS000672080 | N-[[3-(4-fluorophenyl)-1-phenyl-4-pyrazolyl]methyl]-1-phenylmethanamine | N-[[3-(4-fluorophenyl)-1-phenyl-pyrazol-4-yl]methyl]-1-phenyl-methanamine | N-[[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]methyl]-1-phenylmethanamine | N-benzyl-1-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methanamine | SMR000293521 | benzyl-[[3-(4-fluorophenyl)-1-phenyl-pyrazol-4-yl]methyl]amine | cid_1288098 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H20FN3 |
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| Mol. Mass. | 357.4234 |
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| SMILES | Fc1ccc(cc1)-c1nn(cc1CNCc1ccccc1)-c1ccccc1 |
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| Structure | 
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