| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase |
|---|
| Ligand | BDBM64598 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin |
|---|
| EC50 | 17270±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Serine/threonine-protein phosphatase |
|---|
| Name: | Serine/threonine-protein phosphatase |
|---|
| Synonyms: | calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 69558.03 |
|---|
| Organism: | Candida dubliniensis CD36 |
|---|
| Description: | gi_223640082 |
|---|
| Residue: | 607 |
|---|
| Sequence: | MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKY
STVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHL
LSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLL
YLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIM
NEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTN
VVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNY
LDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNV
CTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNP
NTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLH
GVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRL
IRRLSQS
|
|
|
|---|
| BDBM64598 |
|---|
| n/a |
|---|
| Name | BDBM64598 |
|---|
| Synonyms: | 6-bromanyl-3-oxidanyl-2-[3-(trifluoromethyl)phenyl]quinazolin-4-one | 6-bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone | 6-bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4-quinazolinone | 6-bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]quinazolin-4-one | MLS000326257 | SMR000170414 | cid_1487353 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H8BrF3N2O2 |
|---|
| Mol. Mass. | 385.135 |
|---|
| SMILES | On1c(nc2ccc(Br)cc2c1=O)-c1cccc(c1)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
