| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glycogen synthase kinase-3 beta |
|---|
| Ligand | BDBM67851 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Synthase Kinase-3 beta Activity |
|---|
| EC50 | >300000±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Synthase Kinase-3 beta Activity PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Glycogen synthase kinase-3 beta |
|---|
| Name: | Glycogen synthase kinase-3 beta |
|---|
| Synonyms: | GSK-3 beta | GSK-3, beta | GSK3B | GSK3B_HUMAN | Glycogen synthase kinase 3 beta (GSK3B) | Glycogen synthase kinase 3-beta (GSK3B) | Glycogen synthase kinase-3 beta (GSK-3B) | Glycogen synthase kinase-3 beta (GSK3 Beta) | Glycogen synthase kinase-3 beta (GSK3B) | Glycogen synthase kinase-3B (GSK-3B) | Glycogen synthase kinase-3beta (GSK3B) | Serine/threonine-protein kinase GSK3B |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 46756.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49841 |
|---|
| Residue: | 420 |
|---|
| Sequence: | MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST
|
|
|
|---|
| BDBM67851 |
|---|
| n/a |
|---|
| Name | BDBM67851 |
|---|
| Synonyms: | 3-[[3-(4-methoxyphenyl)-1-phenyl-4-pyrazolyl]methylideneamino]-2-sulfanylidene-4-thiazolidinone | 3-[[3-(4-methoxyphenyl)-1-phenyl-pyrazol-4-yl]methyleneamino]-2-thioxo-thiazolidin-4-one | 3-[[3-(4-methoxyphenyl)-1-phenyl-pyrazol-4-yl]methylideneamino]-2-sulfanylidene-1,3-thiazolidin-4-one | 3-[[3-(4-methoxyphenyl)-1-phenylpyrazol-4-yl]methylideneamino]-2-sulfanylidene-1,3-thiazolidin-4-one | 3-{[1-[3-(4-Methoxy-phenyl)-1-phenyl-1H-pyrazol-4-yl]-meth-(E)-ylidene]-amino}-2-thioxo-thiazolidin-4-o ne | MLS000558856 | SMR000149172 | cid_2020650 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H16N4O2S2 |
|---|
| Mol. Mass. | 408.497 |
|---|
| SMILES | COc1ccc(cc1)-c1nn(cc1C=Nn1c(O)csc1=S)-c1ccccc1 |w:14.16| |
|---|
| Structure | 
|
|---|
Search and Browse
