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Reaction Details
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TargetProtein Rev
LigandBDBM67434
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50 17851±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Protein Rev
Name:Protein Rev
Synonyms:Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:PROTEIN
Mol. Mass.:13078.11
Organism:Human immunodeficiency virus 1
Description:ChEMBL_79479
Residue:116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERIL
GTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
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  Blast E-value cutoff:
BDBM67434
n/a
NameBDBM67434
Synonyms:4-amino-2-(3-chlorobenzyl)isoindoline-1,3-quinone | 4-amino-2-[(3-chlorophenyl)methyl]isoindole-1,3-dione | 4-azanyl-2-[(3-chlorophenyl)methyl]isoindole-1,3-dione | MLS000772822 | SMR000377411 | cid_2564389
TypeSmall organic molecule
Emp. Form.C15H11ClN2O2
Mol. Mass.286.713
SMILESNc1cccc2C(=O)N(Cc3cccc(Cl)c3)C(=O)c12
Structure
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