| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM71570 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 3 |
|---|
| IC50 | 2320±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 3 PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42648.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41145 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
|
|
|---|
| BDBM71570 |
|---|
| n/a |
|---|
| Name | BDBM71570 |
|---|
| Synonyms: | 4-[[(3-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-yl-amino]ethyl]benzamide | 4-[[(3-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamide | KSC-5-267B | KUC104150N | N-[2-[benzyl(isopropyl)amino]ethyl]-4-[(m-tolylsulfonylamino)methyl]benzamide | N-[2-[benzyl(propan-2-yl)amino]ethyl]-4-[[(3-methylphenyl)sulfonylamino]methyl]benzamide | cid_44608030 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H33N3O3S |
|---|
| Mol. Mass. | 479.634 |
|---|
| SMILES | CC(C)N(CCNC(=O)c1ccc(CNS(=O)(=O)c2cccc(C)c2)cc1)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
