| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
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| Ligand | BDBM71627 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) |
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| EC50 | >260000±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock factor protein 1 |
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| Name: | Heat shock factor protein 1 |
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| Synonyms: | HSF1_MOUSE | Hsf1 | Hsf1 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57208.68 |
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| Organism: | Mus musculus |
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| Description: | P38532 |
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| Residue: | 525 |
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| Sequence: | MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
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| BDBM71627 |
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| n/a |
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| Name | BDBM71627 |
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| Synonyms: | 7-(2-Chloro-benzyl)-1,3-dimethyl-8-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanyl)-3,7-dihydro-purine-2,6-dione | 7-(2-chlorobenzyl)-1,3-dimethyl-8-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]xanthine | 7-[(2-chlorophenyl)methyl]-1,3-dimethyl-8-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]purine-2,6-dione | 7-[(2-chlorophenyl)methyl]-1,3-dimethyl-8-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]purine-2,6-dione | MLS000075073 | SMR000014924 | cid_646079 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15ClN6O2S2 |
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| Mol. Mass. | 434.923 |
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| SMILES | Cc1nnc(Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc2ccccc2Cl)s1 |
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| Structure | 
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