Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM71727

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM71727

n/a

Name

BDBM71727

Synonyms:

3-[2-(4-chloranylphenoxy)ethylsulfanyl]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole | 3-[2-(4-chlorophenoxy)ethylsulfanyl]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole | 3-[2-(4-chlorophenoxy)ethylthio]-4-ethyl-5-(2-thienyl)-1,2,4-triazole | 3-[2-(4-chlorophenoxy)ethylthio]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole | MLS000057992 | SMR000063033 | cid_2077586

Type

Small organic molecule

Emp. Form.

C16H16ClN3OS2

Mol. Mass.

365.901

SMILES

CCn1c(SCCOc2ccc(Cl)cc2)nnc1-c1cccs1

Structure