Ki Summary

Reaction Details

Report a problem with these data

Target

Heat shock factor protein 1

Ligand

BDBM71781

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM71781

n/a

Name

BDBM71781

Synonyms:

3-[4-oxo-4-(4-phenylpiperazin-1-yl)butyl]-2H-1,2,4-benzothiadiazine 1,1-dioxide | 4-(1,1-diketo-4H-1,2,4-benzothiadiazin-3-yl)-1-(4-phenylpiperazino)butan-1-one | 4-(1,1-dioxo-4H-1,2,4-benzothiadiazin-3-yl)-1-(4-phenyl-1-piperazinyl)-1-butanone | 4-(1,1-dioxo-4H-1,2,4-benzothiadiazin-3-yl)-1-(4-phenylpiperazin-1-yl)butan-1-one | 4-[1,1-bis(oxidanylidene)-4H-1,2,4-benzothiadiazin-3-yl]-1-(4-phenylpiperazin-1-yl)butan-1-one | MLS000094831 | SMR000030384 | cid_3242686

Type

Small organic molecule

Emp. Form.

C21H24N4O3S

Mol. Mass.

412.505

SMILES

O=C(CCCC1=Nc2ccccc2S(=O)(=O)N1)N1CCN(CC1)c1ccccc1 |t:5|

Structure