Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM38824

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM38824

n/a

Name

BDBM38824

Synonyms:

1-(4-methoxybenzyl)-N-(3-morpholin-4-ylpropyl)-5-oxopyrrolidine-3-carboxamide | 1-[(4-methoxyphenyl)methyl]-N-(3-morpholin-4-ylpropyl)-5-oxidanylidene-pyrrolidine-3-carboxamide | 1-[(4-methoxyphenyl)methyl]-N-(3-morpholin-4-ylpropyl)-5-oxopyrrolidine-3-carboxamide | 1-[(4-methoxyphenyl)methyl]-N-[3-(4-morpholinyl)propyl]-5-oxo-3-pyrrolidinecarboxamide | 5-keto-N-(3-morpholinopropyl)-1-p-anisyl-pyrrolidine-3-carboxamide | MLS000046454 | SMR000032465 | cid_3242857

Type

Small organic molecule

Emp. Form.

C20H29N3O4

Mol. Mass.

375.462

SMILES

COc1ccc(CN2CC(CC2=O)C(=O)NCCCN2CCOCC2)cc1

Structure