Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM71789

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM71789

n/a

Name

BDBM71789

Synonyms:

4-(2,5-dichloro-4-methoxy-phenyl)sulfonylpiperazine-1-carboxylic acid ethyl ester | 4-(2,5-dichloro-4-methoxyphenyl)sulfonyl-1-piperazinecarboxylic acid ethyl ester | MLS000085882 | SMR000021211 | cid_1260943 | ethyl 4-(2,5-dichloro-4-methoxyphenyl)sulfonylpiperazine-1-carboxylate | ethyl 4-[(2,5-dichloro-4-methoxyphenyl)sulfonyl]piperazine-1-carboxylate | ethyl 4-[2,5-bis(chloranyl)-4-methoxy-phenyl]sulfonylpiperazine-1-carboxylate

Type

Small organic molecule

Emp. Form.

C14H18Cl2N2O5S

Mol. Mass.

397.274

SMILES

CCOC(=O)N1CCN(CC1)S(=O)(=O)c1cc(Cl)c(OC)cc1Cl

Structure