Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM40311

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM40311

n/a

Name

BDBM40311

Synonyms:

5-[(4-benzofuro[3,2-d]pyrimidinylthio)methyl]-2-furancarboxylic acid methyl ester | 5-[(benzofuro[3,2-d]pyrimidin-4-ylthio)methyl]furan-2-carboxylic acid methyl ester | MLS000087605 | SMR000023827 | cid_2054025 | methyl 5-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanylmethyl)furan-2-carboxylate | methyl 5-[([1]benzofuro[3,2-d]pyrimidin-4-ylthio)methyl]-2-furoate

Type

Small organic molecule

Emp. Form.

C17H12N2O4S

Mol. Mass.

340.353

SMILES

COC(=O)c1ccc(CSc2ncnc3c4ccccc4oc23)o1

Structure