Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM71829

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM71829

n/a

Name

BDBM71829

Synonyms:

2-({1-[2-(methylthio)phenyl]-1H-tetrazol-5-yl}thio)-N-(2-thienylmethyl)acetamide | 2-[1-(2-methylsulfanylphenyl)tetrazol-5-yl]sulfanyl-N-(thiophen-2-ylmethyl)acetamide | 2-[[1-(2-methylsulfanylphenyl)-1,2,3,4-tetrazol-5-yl]sulfanyl]-N-(thiophen-2-ylmethyl)ethanamide | 2-[[1-[2-(methylthio)phenyl]-5-tetrazolyl]thio]-N-(thiophen-2-ylmethyl)acetamide | 2-[[1-[2-(methylthio)phenyl]tetrazol-5-yl]thio]-N-(2-thenyl)acetamide | MLS000051467 | SMR000079828 | cid_2224556

Type

Small organic molecule

Emp. Form.

C15H15N5OS3

Mol. Mass.

377.508

SMILES

CSc1ccccc1-n1nnnc1SCC(=O)NCc1cccs1

Structure