Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM71835

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM71835

n/a

Name

BDBM71835

Synonyms:

2-(5-chloro-2-methoxy-N-methylsulfonylanilino)-N-(2-methylsulfanylphenyl)acetamide | 2-(5-chloro-2-methoxy-N-methylsulfonylanilino)-N-[2-(methylthio)phenyl]acetamide | 2-(5-chloro-N-mesyl-2-methoxy-anilino)-N-[2-(methylthio)phenyl]acetamide | 2-[(5-chloranyl-2-methoxy-phenyl)-methylsulfonyl-amino]-N-(2-methylsulfanylphenyl)ethanamide | MLS000052048 | N~2~-(5-chloro-2-methoxyphenyl)-N~2~-(methylsulfonyl)-N~1~-[2-(methylthio)phenyl]glycinamide | SMR000076874 | cid_2209121

Type

Small organic molecule

Emp. Form.

C17H19ClN2O4S2

Mol. Mass.

414.927

SMILES

COc1ccc(Cl)cc1N(CC(=O)Nc1ccccc1SC)S(C)(=O)=O

Structure