Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM71872

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM71872

n/a

Name

BDBM71872

Synonyms:

4-[2-(diethylamino)-1-oxoethyl]-2-methyl-3-thieno[2,3-b][1,4]benzothiazinecarboxylic acid ethyl ester;hydrochloride | 4-[2-(diethylamino)acetyl]-2-methyl-thieno[2,3-b][1,4]benzothiazine-3-carboxylic acid ethyl ester;hydrochloride | MLS000548192 | SMR000114495 | cid_9549092 | ethyl 4-[(diethylamino)acetyl]-2-methyl-4H-thieno[2,3-b][1,4]benzothiazine-3-carboxylate | ethyl 4-[2-(diethylamino)acetyl]-2-methylthieno[2,3-b][1,4]benzothiazine-3-carboxylate;hydrochloride | ethyl 4-[2-(diethylamino)ethanoyl]-2-methyl-thieno[2,3-b][1,4]benzothiazine-3-carboxylate;hydrochloride

Type

Small organic molecule

Emp. Form.

C20H24N2O3S2

Mol. Mass.

404.546

SMILES

CCOC(=O)c1c(C)sc2Sc3ccccc3N(C(=O)CN(CC)CC)c12

Structure