| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
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| Ligand | BDBM68128 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) |
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| EC50 | 3355±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock factor protein 1 |
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| Name: | Heat shock factor protein 1 |
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| Synonyms: | HSF1_MOUSE | Hsf1 | Hsf1 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57208.68 |
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| Organism: | Mus musculus |
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| Description: | P38532 |
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| Residue: | 525 |
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| Sequence: | MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
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| BDBM68128 |
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| n/a |
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| Name | BDBM68128 |
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| Synonyms: | 1-chloranyl-7,8-bis(fluoranyl)-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | 1-chloro-7,8-difluoro-3-methyl-4-pyrido[1,2-a]benzimidazolecarbonitrile | 1-chloro-7,8-difluoro-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | 1-chloro-7,8-difluoro-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile | MLS000729184 | SMR000307462 | cid_1507407 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H6ClF2N3 |
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| Mol. Mass. | 277.657 |
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| SMILES | Cc1cc(Cl)n2c(nc3cc(F)c(F)cc23)c1C#N |
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| Structure | 
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