| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Eukaryotic translation initiation factor 4H |
|---|
| Ligand | BDBM73179 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis for the identification of translation initiation inhibitors (eIF4H) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Eukaryotic translation initiation factor 4H |
|---|
| Name: | Eukaryotic translation initiation factor 4H |
|---|
| Synonyms: | EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 27385.24 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q15056 |
|---|
| Residue: | 248 |
|---|
| Sequence: | MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM
GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
EVVQKEQE
|
|
|
|---|
| BDBM73179 |
|---|
| n/a |
|---|
| Name | BDBM73179 |
|---|
| Synonyms: | MLS-0356838.0001 | N-(2,5-dimethylphenyl)-1-(2-thenoyl)isonipecotamide | N-(2,5-dimethylphenyl)-1-(thiophene-2-carbonyl)piperidine-4-carboxamide | N-(2,5-dimethylphenyl)-1-[oxo(thiophen-2-yl)methyl]-4-piperidinecarboxamide | N-(2,5-dimethylphenyl)-1-thiophen-2-ylcarbonyl-piperidine-4-carboxamide | cid_778148 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H22N2O2S |
|---|
| Mol. Mass. | 342.455 |
|---|
| SMILES | Cc1ccc(C)c(NC(=O)C2CCN(CC2)C(=O)c2cccs2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
