| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein LANA1 |
|---|
| Ligand | BDBM51281 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction |
|---|
| EC50 | 1620±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Protein LANA1 |
|---|
| Name: | Protein LANA1 |
|---|
| Synonyms: | LANA | LANA1 | LANA1_HHV8P |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 131093.36 |
|---|
| Organism: | Human herpesvirus 8 |
|---|
| Description: | Q9QR71 |
|---|
| Residue: | 1129 |
|---|
| Sequence: | MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPH
TLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPV
SPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPP
EPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWAT
ESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKEC
SENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEED
DEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGD
GNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQRE
PQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQE
PQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQD
EQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEE
QQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQQE
EQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQ
ELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQE
LEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETV
EEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPH
RPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQ
WKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSK
KVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
|
|
|
|---|
| BDBM51281 |
|---|
| n/a |
|---|
| Name | BDBM51281 |
|---|
| Synonyms: | 6-Amino-2-(1,3-dimethyl-1H-pyrazol-4-yl)-benzo[de]isoquinoline-1,3-dione | 6-amino-2-(1,3-dimethyl-4-pyrazolyl)benzo[de]isoquinoline-1,3-dione | 6-amino-2-(1,3-dimethylpyrazol-4-yl)benzo[de]isoquinoline-1,3-dione | 6-amino-2-(1,3-dimethylpyrazol-4-yl)benzo[de]isoquinoline-1,3-quinone | 6-azanyl-2-(1,3-dimethylpyrazol-4-yl)benzo[de]isoquinoline-1,3-dione | MLS001029915 | SMR000426873 | cid_910931 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14N4O2 |
|---|
| Mol. Mass. | 306.3187 |
|---|
| SMILES | Cc1nn(C)cc1N1C(=O)c2cccc3c(N)ccc(C1=O)c23 |
|---|
| Structure | 
|
|---|
Search and Browse
