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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Importin subunit alpha-1 | ||
| Ligand | BDBM75079 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Fluorescence Cell-Free Homogeneous Counterscreen to Identify Inhibitors of the RanGTP-Importin-beta complex. | ||
| EC50 | >500000±n/a nM | ||
| Citation |  PubChem, PC Fluorescence Cell-Free Homogeneous Counterscreen to Identify Inhibitors of the RanGTP-Importin-beta complex. PubChem Bioassay(2010)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Importin subunit alpha-1 | |||
| Name: | Importin subunit alpha-1 | ||
| Synonyms: | IMA1_HUMAN | KPNA2 | RCH1 | SRP1 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 57852.15 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_119609447 | ||
| Residue: | 529 | ||
| Sequence: |
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| BDBM75079 | |||
| n/a | |||
| Name | BDBM75079 | ||
| Synonyms: | (5E)-5-[(1-azepanylamino)methylidene]-1-(1-naphthalenyl)-1,3-diazinane-2,4,6-trione | (5E)-5-[(azepan-1-ylamino)methylene]-1-(1-naphthyl)barbituric acid | (5E)-5-[(azepan-1-ylamino)methylidene]-1-naphthalen-1-yl-1,3-diazinane-2,4,6-trione | 5-[1-(Azepan-1-ylamino)-meth-(E)-ylidene]-1-naphthalen-1-yl-pyrimidine-2,4,6-trione | MLS000332617 | SMR000435975 | cid_5620316 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H22N4O3 | ||
| Mol. Mass. | 378.4244 | ||
| SMILES | Oc1c(C=NN2CCCCCC2)c(=O)[nH]c(=O)n1-c1cccc2ccccc12 |w:4.4,(7.72,1.65,;9.05,.88,;9.05,-.66,;7.72,-1.43,;7.72,-2.97,;6.39,-3.74,;5.11,-2.87,;3.64,-3.33,;3.08,-4.76,;3.85,-6.09,;5.37,-6.32,;6.5,-5.28,;10.39,-1.43,;10.39,-2.97,;11.72,-.66,;11.72,.88,;13.06,1.65,;10.39,1.65,;10.39,3.19,;9.05,3.96,;9.05,5.5,;10.39,6.27,;11.72,5.5,;13.1,6.32,;14.49,5.53,;14.49,3.93,;13.1,3.14,;11.72,3.96,)| | ||
| Structure | 
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