| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 7 |
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| Ligand | BDBM32061 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 |
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| IC50 | 74275±5802 nM |
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| Citation |  PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tyrosine-protein phosphatase non-receptor type 7 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 7 |
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| Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
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| Type: | Protein |
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| Mol. Mass.: | 40530.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35236 |
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| Residue: | 360 |
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| Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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| BDBM32061 |
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| n/a |
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| Name | BDBM32061 |
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| Synonyms: | 1,8-bis(azanyl)-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-3,6-bis(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-3,6-dipyrrolidino-2,7-naphthyridine-4-carbonitrile | MLS000054131 | SMR000061605 | cid_2997948 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21N7 |
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| Mol. Mass. | 323.3955 |
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| SMILES | Nc1nc(cc2c(C#N)c(nc(N)c12)N1CCCC1)N1CCCC1 |
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| Structure | 
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